Pancreatitis
Pancreatitis in Ireland
The prevalence of chronic pancreatitis in Ireland is among the highest in Europe according to clinicians and researchers in Tallaght University Hospital (TUH) and the Department of Surgery in Trinity College Dublin (TCD). Hereditary pancreatitis is defined as inflammation of the pancreas, characterised by recurrent episodes of acute pancreatitis and/or chronic pancreatitis, whereby these pathologies are observed in at least two first degree relatives or at least three second-degree relatives, and are present in two or more generations.
The Eurofins Biomnis panel includes 6 genes: SPINK1, PRSS1, CTRC, CPA1, CFTR and CASR. These genes can be assigned to two categories:
- genes responsible for pancreatitis: PRSS1 and SPINK1 (except the N34S mutation)
- susceptibility genes: CTRC, CPA1, CFTR et CASR and the N34S mutation of SPINK1.
Gene Panel:
Test request Form: https://www.eurofins-biomnis.com/referentiel/liendoc/renseignements/INTGB/B59-INTGB-Pancreatites.pdf
The vast majority of individuals have one or more pharmacogenetic variants. In a study involving
over 1,000 patients1, 99% of them carried at least one genetic variation impacting medication.
Pharmacogenetics (PGx) test:
This test is designed to reduce adverse drug side effects and improve drug efficacy.
Test request form: https://www.eurofins-biomnis.com/referentiel/liendoc/renseignements/INTGB/B110-INTGB-Profil_pharmacogenetique.pdf
