Genetic Testing for Kidney Disease
The Diagnosis of Kidney Disease with a Genetic Origin
According to Study findings from Tilda (2009-2011 ‘Wave 1’ and 2013-2015 ‘Waves 2- 3), 1 in 7 people over 50 years have chronic kidney disease in Ireland, and 98% don’t know they have it. The genetic basis of kidney diseases has evolved since the identification of the autosomal dominant polycystic kidney disease (ADPKD) locus in 1985. Since then, hundreds of different genes involved in kidney disease have been identified.
We have 3 test options in the diagnosis of genetic Kidney Disease and a companion diagnostic, Pharmacogenetics (PGx) test, that helps to reduce adverse side-effects from kidney medications and improve drug efficacy.
Single Gene test:
Hereditary transthyretin amyloidosis (hATTR) is an autosomal dominant disease. It is caused by one or more pathogenic variations in the TTR gene.
Test Request form: https://www.eurofins-biomnis.com/referentiel/liendoc/renseignements/INTGB/B12-INTGB-Molecular_Genetics.pdf
Whole Exome Sequencing test:
Choose WES instead of a gene panel if you suspect a genetic origin but the specific gene(s) are unknown, or when symptoms are unusual or affect multiple organ systems
Read more: https://www.eurofins-biomnis.com/referentiel/liendoc/renseignements/INTGB/DS34-INTGB-Exome.pdf
Test Request form: https://www.eurofins-biomnis.com/referentiel/liendoc/renseignements/INTGB/B34-INTGB-Exome.pdf
MUC1:
Test request form: https://www.eurofins-biomnis.com/referentiel/liendoc/renseignements/INTGB/B12-INTGB-Molecular_Genetics.pdf
Pharmacogenetics (PGx) test:
This test is designed to reduce adverse drug side-effects and improve drug efficacy.
Test request form:https://www.eurofins-biomnis.com/referentiel/liendoc/renseignements/INTGB/B110-INTGB-Profil_pharmacogenetique.pdf
